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• Activity deltas table
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Motif ID: HOX{A4,D4}.p2

Z-value: 0.836

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr13_-_60325073	3.968
chr1_+_84630575	3.148	NM_001242860 NM_001242861	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr2_+_113875469	2.045	NM_000577 NM_173841 NM_173843	IL1RN	interleukin 1 receptor antagonist
chr17_-_39211462	1.982	NM_033032	KRTAP2-2	keratin associated protein 2-2
chr8_+_54764367	1.964	NM_170587	RGS20	regulator of G-protein signaling 20
chr17_-_39525873	1.963	NM_002279	KRT33B	keratin 33B
chr1_-_152386727	1.725	NM_016190	CRNN	cornulin
chr1_+_152881022	1.619	NM_005547	IVL	involucrin
chr7_+_26400503	1.482	NM_001199837	SNX10	sorting nexin 10
chr2_-_31352489	1.473	NM_001253827	GALNT14	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr10_+_118187381	1.372	NM_001011709	PNLIPRP3	pancreatic lipase-related protein 3
chr14_-_81864726	1.345	NM_033104	STON2	stonin 2
chr3_-_74570262	1.339	NM_020872	CNTN3	contactin 3 (plasmacytoma associated)
chr2_+_182850550	1.315	NM_001080545	PPP1R1C	protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr13_-_20805371	1.264	NM_006783	GJB6	gap junction protein, beta 6, 30kDa
chr12_-_89746238	1.255		DUSP6	dual specificity phosphatase 6
chr12_+_8975149	1.223	NM_144670	A2ML1	alpha-2-macroglobulin-like 1
chr12_-_89745997	1.214		DUSP6	dual specificity phosphatase 6
chr2_-_113594325	1.207	NM_000576	IL1B	interleukin 1, beta
chr5_-_147162264	1.185		JAKMIP2	janus kinase and microtubule interacting protein 2
chr13_+_78109808	1.149	NM_001160706 NM_003843 NM_144777	SCEL	sciellin
chr3_-_123339423	1.147	NM_053031 NM_053032	MYLK	myosin light chain kinase
chr6_+_100054649	1.134	NM_021620	PRDM13	PR domain containing 13
chr1_+_151032866	1.125		MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_+_84609941	1.108	NM_182948	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr1_+_151032150	1.099	NM_006818	MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr10_-_105845619	1.095	NM_000494	COL17A1	collagen, type XVII, alpha 1
chr15_+_71433787	1.091	NM_024817	THSD4	thrombospondin, type I, domain containing 4
chr17_+_40703983	1.086	NM_000413	HSD17B1	hydroxysteroid (17-beta) dehydrogenase 1
chr1_+_151032683	1.075		MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr12_+_15699277	1.074	NM_030668 NM_030669 NM_030670 NM_030671	PTPRO	protein tyrosine phosphatase, receptor type, O
chr11_+_125495030	1.071	NM_001114121 NM_001114122 NM_001244846	CHEK1	checkpoint kinase 1
chr17_-_38859976	1.054	NM_019016	KRT24	keratin 24
chr4_-_47983430	1.053	NM_001142564	CNGA1	cyclic nucleotide gated channel alpha 1
chr8_-_27695543	1.047		PBK	PDZ binding kinase
chr2_-_165478357	1.031	NM_004490	GRB14	growth factor receptor-bound protein 14
chr6_+_34206567	1.023	NM_145905	HMGA1	high mobility group AT-hook 1
chr1_+_151032880	1.015		MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr14_-_55650348	1.008		DLGAP5	discs, large (Drosophila) homolog-associated protein 5
chr19_-_36019194	1.008	NM_001166034 NM_001166035 NM_198538	SBSN	suprabasin
chr5_+_52776479	0.998		FST	follistatin
chr16_+_50321822	0.995	NM_001114	ADCY7	adenylate cyclase 7
chr1_-_155948934	0.991		ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr11_-_66675334	0.991	NM_022172	PC	pyruvate carboxylase
chr19_+_15838833	0.987	NM_013939	OR10H2	olfactory receptor, family 10, subfamily H, member 2
chr10_-_105845556	0.987		COL17A1	collagen, type XVII, alpha 1
chr11_-_55703875	0.981	NM_006637	OR5I1	olfactory receptor, family 5, subfamily I, member 1
chr5_+_60933635	0.949	NM_173667	C5orf64	chromosome 5 open reading frame 64
chr12_+_56522049	0.947		ESYT1	extended synaptotagmin-like protein 1
chr1_-_153013593	0.946	NM_006945	SPRR2D	small proline-rich protein 2D
chr7_-_122339186	0.945	NM_139175	RNF133	ring finger protein 133
chr16_-_30124829	0.944	NM_024307	GDPD3	glycerophosphodiester phosphodiesterase domain containing 3
chr12_+_56522043	0.943		ESYT1	extended synaptotagmin-like protein 1
chr12_+_56521953	0.937	NM_001184796 NM_015292	ESYT1	extended synaptotagmin-like protein 1
chr19_+_45409003	0.931	NM_000041	APOE	apolipoprotein E
chr6_-_27880173	0.926	NM_033057	OR2B2	olfactory receptor, family 2, subfamily B, member 2
chr9_+_131185129	0.925		CERCAM	cerebral endothelial cell adhesion molecule
chr7_+_100770378	0.923	NM_000602 NM_001165413	SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr22_+_31478845	0.917	NM_001207017	SMTN	smoothelin
chr3_-_57234279	0.913	NM_003865	HESX1	HESX homeobox 1
chr1_-_149908759	0.904	NM_001145862	MTMR11	myotubularin related protein 11
chr4_+_71200670	0.895	NM_033122	CABS1	calcium-binding protein, spermatid-specific 1
chr17_-_10452939	0.869	NM_001100112 NM_017534	MYH2	myosin, heavy chain 2, skeletal muscle, adult
chr5_+_52776408	0.863		FST	follistatin
chr4_+_1894508	0.862	NM_007331 NM_133330 NM_133331 NM_133335	WHSC1	Wolf-Hirschhorn syndrome candidate 1
chr1_-_149908721	0.860		MTMR11	myotubularin related protein 11
chr3_+_172472246	0.854	NM_018098	ECT2	epithelial cell transforming sequence 2 oncogene
chr17_-_7493389	0.854	NM_006942	SOX15	SRY (sex determining region Y)-box 15
chr5_-_16738346	0.845		MYO10	myosin X
chr7_-_14025826	0.845	NM_001163150 NM_001163151 NM_001163152	ETV1	ets variant 1
chr3_-_123339178	0.843		MYLK	myosin light chain kinase
chr2_-_69098502	0.836	NM_014482	BMP10	bone morphogenetic protein 10
chr17_-_41623652	0.834	NM_001079675	ETV4	ets variant 4
chr19_-_51487070	0.834	NM_139277 NM_001207053 NM_001243126 NM_005046	KLK7	kallikrein-related peptidase 7
chr4_-_159094163	0.828	NM_001031700 NM_001128424	FAM198B	family with sequence similarity 198, member B
chr9_+_75136716	0.825	NM_138691	TMC1	transmembrane channel-like 1
chr10_+_11047253	0.811	NM_001025077	CELF2	CUGBP, Elav-like family member 2
chr2_+_29038862	0.810	NM_001008779	SPDYA	speedy homolog A (Xenopus laevis)
chr11_-_16424391	0.801	NM_001145819 NM_017508	SOX6	SRY (sex determining region Y)-box 6
chr4_+_70796798	0.801	NM_001025104 NM_001890	CSN1S1	casein alpha s1
chr4_-_152147520	0.796	NM_001009555 NM_001128923	SH3D19	SH3 domain containing 19
chr4_+_69313166	0.790	NM_014058	TMPRSS11E	transmembrane protease, serine 11E
chr7_-_92747269	0.787		SAMD9	sterile alpha motif domain containing 9
chr12_-_89746244	0.784	NM_001946 NM_022652	DUSP6	dual specificity phosphatase 6
chr11_-_66639602	0.780
chr1_+_152974222	0.777	NM_001097589 NM_005416	SPRR3	small proline-rich protein 3
chr4_-_159093717	0.776	NM_016613	FAM198B	family with sequence similarity 198, member B
chr18_+_61442611	0.759	NM_003784	SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr4_+_5526882	0.756	NM_005750	C4orf6	chromosome 4 open reading frame 6
chr2_-_208994408	0.755	NM_020989	CRYGC	crystallin, gamma C
chr18_+_61144143	0.746	NM_002639	SERPINB5	serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr10_+_91498724	0.743		KIF20B	kinesin family member 20B
chrX_+_99899162	0.739	NM_014467	SRPX2	sushi-repeat containing protein, X-linked 2
chr2_-_215896809	0.736	NM_015657	ABCA12	ATP-binding cassette, sub-family A (ABC1), member 12
chr10_-_69455926	0.735	NM_013266	CTNNA3	catenin (cadherin-associated protein), alpha 3
chr9_-_95166827	0.733	NM_014057 NM_033014	OGN	osteoglycin
chr14_-_24732344	0.728	NM_000359	TGM1	transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)
chr22_+_38071612	0.718	NM_002305	LGALS1	lectin, galactoside-binding, soluble, 1
chr11_-_7961066	0.717	NM_001003745	OR10A3	olfactory receptor, family 10, subfamily A, member 3
chr6_-_131384321	0.711		EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr20_+_3776385	0.708	NM_004358 NM_021872 NM_021873	CDC25B	cell division cycle 25 homolog B (S. pombe)
chr6_-_41130864	0.706		TREM2	triggering receptor expressed on myeloid cells 2
chr2_-_161056762	0.704		ITGB6	integrin, beta 6
chr11_+_69467210	0.703		CCND1	cyclin D1
chr11_-_67450536	0.700		RPL37	ribosomal protein L37
chr7_-_87342569	0.696	NM_000927	ABCB1	ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr2_-_216003068	0.689	NM_173076	ABCA12	ATP-binding cassette, sub-family A (ABC1), member 12
chr4_-_159093523	0.689		FAM198B	family with sequence similarity 198, member B
chr17_+_7942351	0.681	NM_001039130 NM_001039131 NM_001141	ALOX15B	arachidonate 15-lipoxygenase, type B
chr4_+_95376396	0.680		PDLIM5	PDZ and LIM domain 5
chr9_-_104145800	0.676	NM_001127610	BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr6_-_131384387	0.672	NM_001135554 NM_001135555 NM_001199388 NM_001431	EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr3_+_188664939	0.672		TPRG1	tumor protein p63 regulated 1
chr19_-_51523272	0.665	NM_002776 NM_001077500	KLK10	kallikrein-related peptidase 10
chr13_+_111137249	0.664		COL4A2	collagen, type IV, alpha 2
chr19_-_8642232	0.664		MYO1F	myosin IF
chr15_+_90744506	0.655	NM_198925	SEMA4B	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chrX_-_107681555	0.653	NM_033641	COL4A6	collagen, type IV, alpha 6
chr14_+_23305816	0.649		MMP14	matrix metallopeptidase 14 (membrane-inserted)
chr17_-_39023461	0.648	NM_000223	KRT12	keratin 12
chr8_-_125580745	0.647		MTSS1	metastasis suppressor 1
chr1_+_209859524	0.647	NM_001206741 NM_181755	HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1
chr11_-_69634191	0.646	NM_005247	FGF3	fibroblast growth factor 3
chr2_-_43453146	0.646		ZFP36L2	zinc finger protein 36, C3H type-like 2
chrX_+_99839789	0.645	NM_022144	TNMD	tenomodulin
chr19_+_20959109	0.642
chr2_+_54683276	0.635	NM_003128	SPTBN1	spectrin, beta, non-erythrocytic 1
chr15_-_34610928	0.635	NM_005135	SLC12A6	solute carrier family 12 (potassium/chloride transporters), member 6
chr19_-_51522953	0.632	NM_145888	KLK10	kallikrein-related peptidase 10
chrX_+_48916515	0.631	NM_001163322 NM_033626 NM_001163321 NM_001163323	CCDC120	coiled-coil domain containing 120
chr7_+_77469446	0.629	NM_001127357 NM_001127359 NM_020432	PHTF2	putative homeodomain transcription factor 2
chr22_+_30792929	0.629	NM_001204204 NM_012429 NM_033382	SEC14L2	SEC14-like 2 (S. cerevisiae)
chr1_-_42384370	0.627	NM_001127714 NM_024503	HIVEP3	human immunodeficiency virus type I enhancer binding protein 3
chr8_-_95449131	0.625	NM_001205263	RAD54B	RAD54 homolog B (S. cerevisiae)
chr17_-_39538635	0.624	NM_021013	KRT34	keratin 34
chr1_-_13007405	0.621	NM_001010889	PRAMEF6	PRAME family member 6
chr5_+_140782367	0.610	NM_018921 NM_032089	PCDHGA9	protocadherin gamma subfamily A, 9
chr13_-_24007822	0.607	NM_014363	SACS	spastic ataxia of Charlevoix-Saguenay (sacsin)
chrX_+_37639246	0.602	NM_000397	CYBB	cytochrome b-245, beta polypeptide
chrX_+_79675945	0.599	NM_152630	FAM46D	family with sequence similarity 46, member D
chrX_+_129139163	0.595	NM_021946	BCORL1	BCL6 corepressor-like 1
chrX_+_41548225	0.594	NM_001097579 NM_005300	GPR34	G protein-coupled receptor 34
chr14_+_23305792	0.593	NM_004995	MMP14	matrix metallopeptidase 14 (membrane-inserted)
chr12_+_53443834	0.592	NM_170754	TENC1	tensin like C1 domain containing phosphatase (tensin 2)
chr1_+_40713572	0.592	NM_001008740	TMCO2	transmembrane and coiled-coil domains 2
chr3_+_121774208	0.587	NM_001206924 NM_001206925 NM_175862	CD86	CD86 molecule
chr13_+_43136871	0.584	NM_033012	TNFSF11	tumor necrosis factor (ligand) superfamily, member 11
chr1_+_150245182	0.583	NM_024579	C1orf54	chromosome 1 open reading frame 54
chr5_-_147162251	0.583	NM_014790	JAKMIP2	janus kinase and microtubule interacting protein 2
chr4_+_37962055	0.582	NM_006607	PTTG2	pituitary tumor-transforming 2
chr19_+_8429010	0.570	NM_001039667 NM_139314	ANGPTL4	angiopoietin-like 4
chr2_+_53994928	0.560	NM_001008708	CHAC2	ChaC, cation transport regulator homolog 2 (E. coli)
chr4_-_123377471	0.552	NM_000586	IL2	interleukin 2
chr19_+_45281125	0.551	NM_001130852 NM_012116	CBLC	Cas-Br-M (murine) ecotropic retroviral transforming sequence c
chr1_-_12946024	0.550	NM_001009611	PRAMEF4	PRAME family member 4
chr6_+_32121775	0.543	NM_001204103 NM_005155	PPT2-EGFL8 PPT2	PPT2-EGFL8 readthrough palmitoyl-protein thioesterase 2
chr19_+_49078992	0.541	NM_004605	SULT2B1	sulfotransferase family, cytosolic, 2B, member 1
chrX_+_37639306	0.541		CYBB	cytochrome b-245, beta polypeptide
chr17_-_64225496	0.540	NM_000042	APOH	apolipoprotein H (beta-2-glycoprotein I)
chr6_-_32784727	0.540	NM_002120	HLA-DOB	major histocompatibility complex, class II, DO beta
chr10_+_32856650	0.536	NM_024688	C10orf68	chromosome 10 open reading frame 68
chr16_+_8814567	0.534	NM_001127448	ABAT	4-aminobutyrate aminotransferase
chr12_-_68647225	0.532	NM_020525	IL22	interleukin 22
chr12_-_2986095	0.531		FOXM1	forkhead box M1
chr15_+_52201590	0.531		TMOD3	tropomodulin 3 (ubiquitous)
chr7_+_48128225	0.522	NM_181597	UPP1	uridine phosphorylase 1
chr4_+_84457256	0.521		AGPAT9	1-acylglycerol-3-phosphate O-acyltransferase 9
chr22_+_22758538	0.521
chr11_+_128563993	0.519		FLI1	Friend leukemia virus integration 1
chr15_+_62359175	0.517	NM_207322	C2CD4A	C2 calcium-dependent domain containing 4A
chr11_-_2162340	0.517	NM_001127598	IGF2	insulin-like growth factor 2 (somatomedin A)
chr2_-_165424993	0.516		GRB14	growth factor receptor-bound protein 14
chr2_-_43453737	0.515	NM_006887	ZFP36L2	zinc finger protein 36, C3H type-like 2
chr19_+_11200037	0.514	NM_000527 NM_001195798 NM_001195799 NM_001195800 NM_001195802 NM_001195803	LDLR	low density lipoprotein receptor
chr12_-_7656285	0.513	NM_004244 NM_203416	CD163	CD163 molecule
chr4_-_48014960	0.512	NM_000087	CNGA1	cyclic nucleotide gated channel alpha 1
chr6_-_42110714	0.510	NM_001164446	C6orf132	chromosome 6 open reading frame 132
chr1_-_17308072	0.508	NM_001135247 NM_017459	MFAP2	microfibrillar-associated protein 2
chr7_+_151653463	0.508	NM_145292	GALNTL5	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5
chr12_+_27677044	0.506	NM_001198915 NM_001198916 NM_003622 NM_177444	PPFIBP1	PTPRF interacting protein, binding protein 1 (liprin beta 1)
chrX_-_100872926	0.503	NM_001009584 NM_001184768 NM_019007	ARMCX6	armadillo repeat containing, X-linked 6
chrX_+_135251454	0.500	NM_001159704	FHL1	four and a half LIM domains 1
chr4_-_156787377	0.497	NM_017419	ACCN5	amiloride-sensitive cation channel 5, intestinal
chr1_+_8384389	0.496	NM_001080397	SLC45A1	solute carrier family 45, member 1
chr1_-_150978879	0.496	NM_001163259 NM_001163260 NM_001040217	FAM63A	family with sequence similarity 63, member A
chr6_-_42162693	0.495	NM_002098	GUCA1B	guanylate cyclase activator 1B (retina)
chr19_-_39443326	0.490	NM_148169	FBXO17	F-box protein 17
chr10_-_101841593	0.486	NM_001308	CPN1	carboxypeptidase N, polypeptide 1
chr3_-_138478184	0.486	NM_006219	PIK3CB	phosphoinositide-3-kinase, catalytic, beta polypeptide
chr19_+_45417920	0.485	NM_001645	APOC1	apolipoprotein C-I
chr5_-_16742336	0.483		MYO10	myosin X
chr4_-_65275000	0.477	NM_001010874	TECRL	trans-2,3-enoyl-CoA reductase-like
chr22_-_42336222	0.475	NM_001110215	CENPM	centromere protein M
chr7_-_107443631	0.475	NM_000111	SLC26A3	solute carrier family 26, member 3
chr16_+_68877492	0.470	NM_024562	TMCO7	transmembrane and coiled-coil domains 7
chr7_-_86595203	0.467	NM_152748	KIAA1324L	KIAA1324-like
chr4_+_169013687	0.466	NM_007193	ANXA10	annexin A10
chr1_-_153348057	0.466	NM_005621	S100A12	S100 calcium binding protein A12
chr3_-_165555252	0.465	NM_000055	BCHE	butyrylcholinesterase
chr6_-_138820578	0.464	NM_001144060	NHSL1	NHS-like 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.47	2.18e-02	GO:0009611	response to wounding
1.16	4.25e-02	GO:0032501	multicellular organismal process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.34	6.43e-05	GO:0005576	extracellular region
1.49	1.50e-04	GO:0044421	extracellular region part
1.53	8.04e-04	GO:0005615	extracellular space
2.59	3.30e-02	GO:0042383	sarcolemma

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.64	1.93e-03	GO:0008092	cytoskeletal protein binding
1.53	1.73e-02	GO:0005198	structural molecule activity